I don't agree with some of the statements above.
A little suggested reading on setting amplifier gain controls.
http://www.rane.com/note135.html
IMHO:
When using digital components it is suggested to use maximum levels in the pre-amp/active crossovers and set the amps accordingly.
Setting up my system gain structure as decribed in this tech note lowered the noise floor considerably. My tweeters had alot of hiss before and none is perceptable now.
An amplifier will provide rated output at a given input voltage where ever the antenuators are positioned.