Thanks Doctor_Electron. I'll take some time and do the math laid out in the link you provided. I had also seen the enclosure guide and I have seen a lot of JBL 4320 that were converted to 4333's that retain both ports.
Without much else to go on, I had decided to go with the same ports that the original 4333 had since it has the same volume box. So I went from (2) 7" ports to a single 4" port - same as 4333. I blocked the other port but if I wanted to, I could just unseal it and reinstall the ports which I have still retained.
not sure how I will test how effective the single port is but I guess we'll see soon.