The ADC’s today are so good so you won’t lose much there compared to the advantage to be able to correct frequency response, phase and timing. One needs to pick the battles.
If you decide to go the BSS route the London Soundweb units can be equipped with digital input and digital output to allow use of your favourite DAC’s. They can do balanced (or single end) SPDIF and AES in and out.
Regarding clocking I wrote some thoughts here.