I have a pair of Bag End S18E-I cabinets and an ELF M2. (Now they call them INFRA units.) My understanding is that the Bag End ELF drivers have a very high resonant frequency. The cabinets are relatively small (around 3.8 cu ft) and sealed. The ELF "integrator" is a fancy EQ that boosts the bejesus out of the low end. I use a Krell KSA 300s to drive them and they go waaaaay deep.
I guess you could use a 2245 in such a setup, but there is no guarantee that it would work. However, you might wind up overdriving it below its resonant frequency and damage it.