I generally run flat on my active set-up except for the last octave 40Hz and down where the subs run. Those levels are up a bit mainly from room loading. If I run them flat they don't blend right with the E-145's and it sounds a bit lean.
I think most people are used to some bass bloom and when you do run flat it can take a little getting used to. The advantages are the tonality and clarity are much improved with good source material.My Dynaudio/2245H sub system is flat below 200 hz, and mostly sounds lean without a couple db of boost below 160hz...but it is in a fairly large L shaped space.
The 4344's on my second system are run with no EQ what so ever. Between room placement and careful set-up on the individual driver balance I didn't think they really needed any.
Rob