Hello
The DBX Zone Pro units would be the ultimate for simple operation. The 641 model has no contols at all and is complety programed via a PC. You can add optional external controls such a volume, source select ect. I have used four of the Zone Pro units in different installations and they have been fool proof! You can configure them in just about any possiable way you could imagine. They can do all of processing as well, crossover, eq, limiting, mic ducking so when they talk into a mic the music level will be reduced to a preset level. They have two mic inputs and standard line inputs on RCA jacks.
There kinda like a BSS soundweb only less expensive.
Heres the link to the DBX site http://www.dbxpro.com/640.htm
Down load the operation software and you can get a feel for what they can do.
Mike Caldwell